甲基化样蛋白11抗体（N端）

产品货号：

BN41188R
中文名称：

甲基化样蛋白11抗体（N端）
英文名称：

Rabbit anti-METTL11A Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41188R-100ul

100ul

¥2360.00

交叉反应：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse) 推荐应用：IHC-P,IHC-F,IF,ELISA
BN41188R-200ul

200ul

¥3490.00

交叉反应：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse) 推荐应用：IHC-P,IHC-F,IF,ELISA

产品描述

英文名称	METTL11A
中文名称	甲基化样蛋白11抗体（N端）
别名	Methyltransferase like 11A; Methyltransferase-like protein 11A; Mettl11a; N-terminal RCC1 methyltransferase; NRMT; NTM1A; NTM1A_HUMAN; NTMT1; X-Pro-Lys N-terminal protein methyltransferase 1A; AD 003; Alpha N-terminal protein methyltransferase 1A; C9orf32; Chromosome 9 open reading frame 32.
研究领域	细胞生物免疫学细胞周期蛋白细胞分化
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, )
产品应用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	25kDa
细胞定位	细胞核
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human METTL11A:25-130/223
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala, Pro or Ser residue in the [Ala/Pro/Ser]-Pro-Lys motif. Mediates the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation. Function: Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1. Subcellular Location: Nucleus. Note=Predominantly nuclear. Similarity: Belongs to the methyltransferase superfamily. NTM1 family. SWISS: Q9BV86 Gene ID: 28989 Database links: Entrez Gene: 28989 Human Entrez Gene: 66617 Mouse Entrez Gene: 362103 Rat Omim: 613560 Human SwissProt: Q9BV86 Human SwissProt: Q8R2U4 Mouse SwissProt: Q5BJX0 Rat Unigene: 522433 Human Unigene: 33167 Mouse Unigene: 12306 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.