货号
产品规格
售价
备注
BN41183R-100ul
100ul
¥2360.00
交叉反应：Human(predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41183R-200ul
200ul
¥3490.00
交叉反应：Human(predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | AARE |
| 中文名称 | 氧化蛋白质水解酶 |
| 别 名 | AARE; ACPH; Acyl peptide hydrolase; Acylamino acid releasing enzyme; Acylaminoacyl peptidase; APEH; APH; D3F15S2; D3S48E; DNF15S2; N acylaminoacyl peptide hydrolase; OPH; Oxidized protein hydrolase; ACPH_HUMAN. |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 81kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AARE:101-200/732 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Subunit: Interacts with SUV420H1, SUV420H2 and USP4 Subcellular Location: Nucleus. Similarity: Belongs to the retinoblastoma protein (RB) family. SWISS: P13798 Gene ID: 327 Database links: Entrez Gene: 327 Human Entrez Gene: 235606 Mouse GenBank: 33875348 Human Omim: 102645 Human SwissProt: P13798 Human SwissProt: Q8R146 Mouse Unigene: 517969 Human Unigene: 219639 Mouse Unigene: 11057 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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