鳞状细胞癌增强蛋白1抗体

产品货号：

BN40684R
中文名称：

鳞状细胞癌增强蛋白1抗体
英文名称：

Rabbit anti-GASC1/KDM4C Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN40684R-100ul

100ul

¥2360.00

交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA
BN40684R-200ul

200ul

¥3490.00

交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA

产品描述

英文名称	GASC1/KDM4C
中文名称	鳞状细胞癌增强蛋白1抗体
别名	GASC 1 protein; GASC1 antibody Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain containing histone demethylation protein 3C; Jumonji domain containing protein 2C; KDM4C_HUMAN.
研究领域	肿瘤免疫学染色质和核信号
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用	WB=1:500-2000 ELISA=1:500-5000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	120kDa
细胞定位	细胞核
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GASC1/KDM4C:291-390/1056
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	KDM4C/JMJD2C, a jumonji domain containing protein, is a histone demethylase. JMJD2C specifically demethylates Lysine 9 and Lysine 36 residues of Histone H3, thereby playing a central role in regulating histone modifications. Function: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Subcellular Location: Nucleus. Tissue Specificity: Overexpressed in several esophageal squamous cell carcinomas (ESCs). Similarity: Belongs to the JHDM3 histone demethylase family. Contains 1 JmjC domain. Contains 1 JmjN domain. Contains 2 PHD-type zinc fingers. Contains 2 Tudor domains. SWISS: Q9H3R0 Gene ID: 23081 Database links: Entrez Gene: 23081 Human Entrez Gene: 76804 Mouse Entrez Gene: 298144 Rat Omim: 605469 Human SwissProt: Q9H3R0 Human SwissProt: Q8VCD7 Mouse Unigene: 709425 Human Unigene: 209059 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.