溶血磷脂酸受体蛋白2抗体

产品货号：

BN40246R
中文名称：

溶血磷脂酸受体蛋白2抗体
英文名称：

Rabbit anti-LPA2 Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN40246R-100ul

100ul

¥2360.00

交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN40246R-200ul

200ul

¥3490.00

交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

产品描述

英文名称	LPA2
中文名称	溶血磷脂酸受体蛋白2抗体
别名	Endothelial Cell Differentiation Gene 4; Endothelial differentiation lysophosphatidic acid G protein coupled receptor 4; IPA2; LPA receptor 2; LPA receptor EDG4; LPA2; LPAR2; Lysophosphatidic acid receptor Edg4; Edg4; LPAR2_HUMAN.
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	39kDa
细胞定位	细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human LPA2:1-100/351 <Extracellular>
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] Function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. Subunit: Interacts with SLC9A3R2/NHERF2, MAGI3 and PLCB3. Interacts with RALA and ADRBK1. Subcellular Location: Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles. Tissue Specificity: Expressed most abundantly in testes and peripheral blood leukocytes with less expression in pancreas, spleen, thymus and prostate. Little or no expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney, ovary, small intestine, or colon. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q9HBW0 Gene ID: 9170 Database links: Entrez Gene: 9170 Human Entrez Gene: 53978 Mouse Omim: 605110 Human SwissProt: Q9HBW0 Human SwissProt: Q9JL06 Mouse Unigene: 122575 Human Unigene: 23253 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.