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转铁蛋白单克隆抗体
  • 产品货号:
    BN42029M
  • 中文名称:
    转铁蛋白单克隆抗体
  • 英文名称:
    Mouse anti-Transferrin Monoclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN42029M-50ul

    50ul

    ¥1486.00

    交叉反应:Human 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN42029M-100ul

    100ul

    ¥2360.00

    交叉反应:Human 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN42029M-200ul

    200ul

    ¥3490.00

    交叉反应:Human 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

产品描述

英文名称Transferrin
中文名称转铁蛋白单克隆抗体
别    名Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin; TRFE_HUMAN; Beta-1 metal-binding globulin; Serotransferrin.  
研究领域心血管  
抗体来源Mouse
克隆类型Monoclonal
克 隆 号12D9
交叉反应Human, 
产品应用WB=1:500-1000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量77kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原Full length native Transferrin protein purified from human plasma: 
亚    型IgG
纯化方法affinity purified by Protein G
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009].

Function:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

DISEASE:
Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.

Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.

SWISS:
P02787

Gene ID:
7018

Database links:

Entrez Gene: 7018 Human

Entrez Gene: 22041 Mouse

Entrez Gene: 24825 Rat

Omim: 190000 Human

SwissProt: P02787 Human

SwissProt: Q921I1 Mouse

SwissProt: P12346 Rat

Unigene: 518267 Human

Unigene: 37214 Mouse

Unigene: 91296 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.