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首页>>免疫学>>一抗>>膜糖蛋白CD200抗体
膜糖蛋白CD200抗体
  • 产品货号：
    BN41932R
  • 中文名称：
    膜糖蛋白CD200抗体
  • 英文名称：
    Rabbit anti-CD200 Polyclonal antibody
  • 品牌：
    Biorigin

  • 货号

    产品规格

    售价

    备注

  • BN41932R-50ul

    50ul

    ¥1486.00

    交叉反应：Human,Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,IF,ELISA

  • BN41932R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,IF,ELISA

  • BN41932R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,IF,ELISA

产品描述

英文名称CD200
中文名称膜糖蛋白CD200抗体
别    名CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G_HUMAN.  


研究领域细胞生物  免疫学  细胞表面分子  糖蛋白  淋巴细胞  t-淋巴细胞  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量28kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CD200:41-140/278 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Function:
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

Subunit:
Interacts with CD200R1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P41217

Gene ID:
4345

Database links:

Entrez Gene: 4345 Human

Omim: 155970 Human

SwissProt: P41217 Human

Unigene: 79015 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD200是Ⅰ型膜糖蛋白，为免疫球蛋白超家族的新成员，广泛表达在人类胸腺细胞、B细胞、激活的T细胞、滤泡状树突细胞、神经元及血管内皮上。可表达于B细胞及其增殖性疾病和一部分T细胞。近年来研究发现，CD200与CD200R间的相互作用可以传递抑制性信号减低髓样细胞的活性，改变其迁移。CD200在免疫疾病和抑制排斥反应中作为一种免疫耐受信号，它的一些相关分子在免疫调节中也具有一定的作用。