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BN41926R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41926R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41926R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | ADAM23 |
| 中文名称 | 去整合素样金属蛋白酶23抗体 |
| 别 名 | A disintegrin and metalloproteinase domain 23; MDC 3; Metalloproteinase like disintegrin like and cysteine rich protein 3. |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 75-95kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ADAM23:551-650/832 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions. Subunit: Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Isoform Gamma: Secreted. Tissue Specificity: Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. Similarity: Contains 1 disintegrin domain. Contains 1 EGF-like domain. Contains 1 peptidase M12B domain. SWISS: O75077 Gene ID: 8745 Database links: Entrez Gene: 8745 Human Entrez Gene: 23792 Mouse Omim: 603710 Human SwissProt: O75077 Human SwissProt: Q9R1V7 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 细胞外基质蛋白 |
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