货号
产品规格
售价
备注
BN41924R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推荐应用：WB,IF,Flow-Cyt,ELISA
BN41924R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推荐应用：WB,IF,Flow-Cyt,ELISA
BN41924R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推荐应用：WB,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | MCPIP1 |
| 中文名称 | 单核细胞趋化诱导蛋白1抗体 |
| 别 名 | dJ423B22.1; MCP 1 treatment-induced protein; MCP-induced protein 1; MCPIP 1; MCPIP; Ribonuclease ZC3H12A; RP3-423B22.1; ZC12A_HUMAN; ZC3H 12A; ZC3H12 A; Zc3h12a; Zinc finger CCCH domain-containing protein 12A; Zinc finger CCCH type containing 12A. |
| 研究领域 | 肿瘤 心血管 细胞生物 免疫学 染色质和核信号 信号转导 细胞凋亡 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, Chicken, Dog, Cow, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 66kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MCPIP1:201-300/599 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. Function: Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the ZC3H12 family. Contains 1 C3H1-type zinc finger. SWISS: Q5D1E8 Gene ID: 80149 Database links: Entrez Gene: 80149 Human Entrez Gene: 230738 Mouse Omim: 610562 Human SwissProt: Q5D1E8 Human SwissProt: Q5D1E7 Mouse Unigene: 656294 Human Unigene: 402 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在线咨询
English
