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产品规格
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BN41919R-50ul
50ul
¥1486.00
交叉反应:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41919R-100ul
100ul
¥2360.00
交叉反应:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41919R-200ul
200ul
¥3490.00
交叉反应:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
英文名称 | SAHH |
中文名称 | S腺苷L-同型半胱氨酸水解酶抗体 |
别 名 | Adenosylhomocysteinase; AdoHcyase; ahcY; S adenosyl L homocysteine hydrolase; S adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; SAHH_HUMAN. |
研究领域 | 肿瘤 细胞生物 免疫学 信号转导 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 48kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SAHH:25-125/432 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Function: Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Subunit: Homotetramer. Subcellular Location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. DISEASE: Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) [MIM:613752]. A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy. Similarity: Belongs to the adenosylhomocysteinase family. SWISS: P23526 Gene ID: 191 Database links: Entrez Gene: 191 Human Entrez Gene: 269378 Mouse Omim: 180960 Human SwissProt: P23526 Human SwissProt: P50247 Mouse Unigene: 388004 Human Unigene: 330692 Mouse Unigene: 371964 Mouse Unigene: 5878 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |