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产品规格
售价
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BN41872R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41872R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41872R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | BRN3A |
| 中文名称 | 转录因子Brn3蛋白抗体 |
| 别 名 | Brain specific homeobox/POU domain protein 3A; Brn 3.0; BRN 3A; Brn3; Homeobox/POU domain protein RDC 1; Homeobox/POU domain protein RDC1; Oct T1; OctT1; POU Domain Class 4 Transcription Factor 1; POU4F1; RDC 1; RDC1. |
| 研究领域 | 免疫学 神经生物学 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BRN3A:325-419/419 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012]. Function: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Subcellular Location: Nucleus. Tissue Specificity: Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye. DISEASE: Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth. Similarity: Belongs to the POU transcription factor family. Class-4 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. SWISS: Q01851 Gene ID: 5457 Database links: Entrez Gene: 5457 Human Entrez Gene: 18996 Mouse Omim: 601632 Human SwissProt: Q01851 Human SwissProt: P17208 Mouse Unigene: 654522 Human Unigene: 246550 Mouse Unigene: 232568 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 转录因子Brn3可能直接参与对轴突和树突生长能力的调控。 |
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