免疫球蛋白G Fc段受体I

产品货号：

BN41862R
中文名称：

免疫球蛋白G Fc段受体I
英文名称：

Rabbit anti-FCGR1A/CD64 Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41862R-50ul

50ul

¥1486.00

交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,ICC,ELISA

产品描述

英文名称	FCGR1A/CD64
中文名称	免疫球蛋白G Fc段受体I
别名	CD 64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ia receptor; F Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for; Fc fragment of IgG, high affinity Ib, receptor (CD64); Fc fragment of IgG, high affinity Ib, receptor for; Fc fragment of IgG, high affinity Ic, receptor (CD64); Fc fragment of IgG, high affinity Ic, receptor for; Fc gamma receptor; Fc gamma receptor I A1; Fc gamma receptor I; Fc gamma receptor I B2; Fc gamma RI; Fc of IgG high affinity Ia receptor; Fc-gamma RIC; FCG 1; FCG1; FcgammaRI; FCGR 1; FCGR1; FCGR1A; FCGR1B; FCGR1C; FcRI; FCRIC; IGFR 1; IGFR1; IGFRB; IGFRC; IgG Fc receptor I; IgG Fc receptor IC; Immunoglobulin G Fc receptor I; Immunoglobulin G Fc receptor IB; Immunoglobulin G Fc receptor IC.
研究领域	细胞生物免疫学细胞膜受体细胞表面分子
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, (predicted: Rat, Pig, Cow, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1μg /test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	41kDa
细胞定位	细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human CD64/IGFR1:101-200/374 <Extracellular>
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	The high affinity receptor for immunoglobulin G CD64 is encoded by a family of 3 genes that share over 98% of DNA sequence homology: FCGR1A, FCGR1B and FCGR1C. The FCGR1C gene, like FCGR1A, is located on 1q21. The third gene of this family, FCGR1B, was found at 1p12. CD64 plays a pivotal role in the immune response. It is a glycoprotein (MW 72 kD) that is constitutively expressed on human monocytes and macrophages. Subunit: Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL. Interacts with HCK and LYN. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Note=Stabilized at the cell membrane through interaction with FCER1G. Tissue Specificity: Monocyte/macrophage specific. Similarity: Belongs to the immunoglobulin superfamily. FCGR1 family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. SWISS: P12314 Gene ID: 2209 Database links: Entrez Gene: 2209 Human Omim: 146760 Human SwissProt: P12314 Human Unigene: 77424 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD64是一种糖蛋白，主要定位于单核细胞和巨噬细胞,参与免疫应答反应。