货号
产品规格
售价
备注
BN41805R-50ul
50ul
¥1486.00
交叉反应：Mouse,Rat 推荐应用：WB,IHC-P
BN41805R-100ul
100ul
¥2360.00
交叉反应：Mouse,Rat 推荐应用：WB,IHC-P
BN41805R-200ul
200ul
¥3490.00
交叉反应：Mouse,Rat 推荐应用：WB,IHC-P
产品描述
| 英文名称 | RSL1D1 |
| 中文名称 | 细胞衰老抑制基因抗体 |
| 别 名 | CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; L12; PBK1; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; Ribosomal L1 domain containing 1. |
| 研究领域 | 肿瘤 染色质和核信号 信号转导 细胞周期蛋白 转录调节因子 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | WB=1:500-2000 IHC-P=1:400-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 55kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse RSL1D1:311-410/452 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | RSL1D1, also known as CATX-11, PBK1, L12 or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family. Expressed in placenta, RSL1D1 contains many phosphorylated amino acid residues and is encoded by a gene that maps to human chromosome 16p13.13. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Subcellular Location: Nucleus, nucleolus. Tissue Specificity: Placenta. Similarity: Belongs to the ribosomal protein L1P family. Highly divergent. SWISS: Q8BVY0 Gene ID: 66409 Database links: Entrez Gene: 26156 Human SwissProt: O76021 Human Unigene: 401842 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CSIG可抑制细胞衰老并延长细胞寿命 ,可能通过核糖体生物合成过程或基因转录调节来调控细胞衰老过程. |
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