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产品规格
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BN41729R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41729R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41729R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | NCX1 |
| 中文名称 | 钠钙交换蛋白1抗体 |
| 别 名 | Na+/Ca2+exchanger 1; CNC; DKFZp779F0871; MGC119581; FLJ37694; FLJ43417; Na+/Ca2+ exchange protein 1; Na+/Ca2+ exchanger; NCX 1; NCX; SLC8A1; SLC8A1 protein; Sodium Calcium Exchanger; Sodium/calcium exchanger 1; Solute carrier family 8 member 1; NAC1_HUMAN. |
| 研究领域 | 肿瘤 免疫学 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 106kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NCX1:801-900/971 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma(plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM]. Subcellular Location: Cell membrane. Tissue Specificity: Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung. Similarity: Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. Contains 2 Calx-beta domains. SWISS: P32418 Gene ID: 6546 Database links: Entrez Gene: 6546 Human Entrez Gene: 20541 Mouse Entrez Gene: 100328570 Rabbit Omim: 182305 Human SwissProt: P48766 Guinea pig SwissProt: P32418 Human SwissProt: P70414 Mouse Unigene: 31961 Human Unigene: 468274 Human Unigene: 728911 Human Unigene: 265834 Mouse Unigene: 118972 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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