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BN41720R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Cow,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41720R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Cow,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41720R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Cow,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | PAFR/PAF Receptor |
| 中文名称 | 血小板活化因子受体抗体 |
| 别 名 | Platelet-activating factor receptor; PAF receptor; Ptafr; OTTHUMP00000004041; OTTMUSP00000010350; PAF R; PAF-R; PAFR; Platelet activating factor receptor; Platelet-activating factor receptor; PTAFR; PTAFR_HUMAN; RP23-470B20.1. |
| 研究领域 | 心血管 细胞生物 免疫学 神经生物学 信号转导 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Cow, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1µg/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAFR:231-342/342 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes. The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically. Function: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. Subunit: Interacts with ARRB1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P25105 Gene ID: 5724 Database links: Entrez Gene: 5724 Human Entrez Gene: 19204 Mouse Omim: 173393 Human SwissProt: P25105 Human SwissProt: Q62035 Mouse SwissProt: P35366 Rhesus monkey Unigene: 433540 Human Unigene: 725944 Human Unigene: 89389 Mouse Unigene: 10137 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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