货号
产品规格
售价
备注
BN41694R-50ul
50ul
¥1486.00
交叉反应：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推荐应用：IHC-P,IHC-F,IF,ELISA
BN41694R-100ul
100ul
¥2360.00
交叉反应：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推荐应用：IHC-P,IHC-F,IF,ELISA
BN41694R-200ul
200ul
¥3490.00
交叉反应：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推荐应用：IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | FAF1 |
| 中文名称 | Fas相关1因子抗体 |
| 别 名 | Fas associated factor 1; CGI; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; CGI 03; FAF1; FAF1_HUMAN; Fas associated protein factor 1; FAS-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A; TNFRSF6 associated factor 1. |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rat, (predicted: Mouse, Chicken, Dog, Cow, Rabbit, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 74kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAF1:551-650/650 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. It is transiently expressed in T cells and potentiates Fas-induced apoptosis. FAF1 lacks a DDH (Death domain homologous region), in contrast to TRADD, FADD, and RIP, and cannot induce apoptosis independent of Fas activation. Fas associated factor 1; CGI ; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; TNFRSF6 associated factor 1. Function: Potentiates but cannot initiate FAS-induced apoptosis. Subunit: Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain. Subcellular Location: Nucleus. Tissue Specificity: Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes. Similarity: Contains 1 UBA domain. Contains 1 UBX domain. SWISS: Q9UNN5 Gene ID: 11124 Database links: Entrez Gene: 11124 Human Entrez Gene: 14084 Mouse Omim: 604460 Human SwissProt: Q9UNN5 Human SwissProt: P54731 Mouse Unigene: 530402 Human Unigene: 318259 Mouse Unigene: 198288 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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