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催产素受体(缩宫素受体)抗体
  • 产品货号:
    BN41686R
  • 中文名称:
    催产素受体(缩宫素受体)抗体
  • 英文名称:
    Rabbit anti-Oxytocin R Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

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  • BN41686R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推荐应用:WB,IHC-P,ELISA

  • BN41686R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推荐应用:WB,IHC-P,ELISA

  • BN41686R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推荐应用:WB,IHC-P,ELISA

产品描述

英文名称Oxytocin R
中文名称催产素受体(缩宫素受体)抗体
别    名Oxytocin R; OT R; OT-R; OTR 1; OTR; OTR1; OXT R; OXTR; Oxytocin receptor; OXYR_HUMAN.  
研究领域神经生物学  生长因子和激素  细胞膜受体  内分泌病  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量43kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse oxytocin receptor:325-388/388 <Cytoplasmic>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. Oxytocin receptor has been reported in breast, central nervous system, heart, ovary, placenta, prostate, salivary gland, testis, uterus, and vessel.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

SWISS:
P97926

Gene ID:
18430

Database links:

Entrez Gene: 281371 Cow

Entrez Gene: 5021 Human

Entrez Gene: 18430 Mouse

Entrez Gene: 397092 Pig

Entrez Gene: 25342 Rat

Omim: 167055 Human

SwissProt: P56449 Cow

SwissProt: P30559 Human

SwissProt: P97926 Mouse

SwissProt: P32306 Pig

SwissProt: P70536 Rat

SwissProt: Q28756 Sheep

Unigene: 2820 Human

Unigene: 333310 Mouse

Unigene: 6841 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OTR在人的子宫平滑肌细胞膜上有缩宫素受体,缩宫素引起子宫收缩的机制可能是通过激活缩宫素受体而实现的。经研究发现,缩宫素受体在外周组织和中枢神经系统内均有分布。缩宫素与不同组织、细胞上的缩宫素受体结合,通过多种信号转导途径而发挥作用。