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5-羟色胺受体2A抗体
  • 产品货号:
    BN41639R
  • 中文名称:
    5-羟色胺受体2A抗体
  • 英文名称:
    Rabbit anti-5HT2A Receptor Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN41639R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat 推荐应用:WB,IHC-F,IF,ELISA

  • BN41639R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat 推荐应用:WB,IHC-F,IF,ELISA

  • BN41639R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat 推荐应用:WB,IHC-F,IF,ELISA

产品描述

英文名称5HT2A Receptor
中文名称5-羟色胺受体2A抗体
别    名5-hydroxytryptamine receptor 2A; 5-hydroxytryptamine receptor; Serotonin receptor 2A; 5-HT-2A; 5-HT-2; HTR2A; Htr2a; 5 HT 2; 5HTR2A; 5 HT 2A; 5 HT2 receptor; 5 HT2A; 5 hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; 5-hydroxytryptamine 2A receptor; 5-hydroxytryptamine receptor 2A; 5HT2A_HUMAN; HTR 2; HTR 2A; HTR2; HTR2A. 



研究领域神经生物学  通道蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, 
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=3ug/Test IF=1:200-800 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量52kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human 5HT2A Receptor:65-160/471 <Cytoplasmic>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍5HT2A receptor is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5HT2A receptor belongs to the G-protein coupled receptor 1 family and mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. 5HT2A receptor is an integral membrane protein which localizes to the post-synaptic thickening of axo-dendritic synapses. 5HT2A receptor protein contains a PDZ domain-binding motif which is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

Subunit:
Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Note=Localizes to the postsynaptic thickening of axo-dendritic synapses.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P28223

Gene ID:
3356

Database links:

Entrez Gene: 3356 Human

Entrez Gene: 15558 Mouse

Entrez Gene: 29595 Rat

Omim: 182135 Human

SwissProt: P28223 Human

SwissProt: P35363 Mouse

SwissProt: P14842 Rat

Unigene: 654586 Human

Unigene: 72630 Human

Unigene: 214351 Mouse

Unigene: 10294 Rat

Unigene: 146756 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.