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产品规格
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BN41614R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41614R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41614R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | Dopamine Receptor D1 |
| 中文名称 | 多巴胺受体D1抗体 |
| 别 名 | DRD1; dopamine D1 receptor; D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine Receptor D1; DR D1; DR D1A; DRD 1; DRD1 receptor; DRD1; DRD1A; DRD1_HUMAN; D(1A) dopamine receptor; DRD 1A; DRD1. |
| 研究领域 | 肿瘤 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DRD1:101-200/446 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008] Function: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Subunit: Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Detected in caudate, nucleus accumbens and in the olfactory tubercle. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P21728 Gene ID: 1812 Database links: Entrez Gene: 1812 Human Entrez Gene: 13488 Mouse Omim: 126449 Human SwissProt: P21728 Human SwissProt: Q61616 Mouse Unigene: 2624 Human Unigene: 54161 Mouse Unigene: 24039 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 多巴胺受体D1在运动协调方面起重要作用，该受体的缺失对黑质多巴胺能神经元的影响程度虽没临床帕金森病（PD）严重，但仍可加速多巴胺能神经元发生退行性改变.该蛋白目前主要用于神经退行性改变的研究。 |
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