货号
产品规格
售价
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BN41608R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,ELISA
BN41608R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,ELISA
BN41608R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,ELISA
产品描述
| 英文名称 | NCR1 |
| 中文名称 | 细胞毒性受体NK-p46抗体 |
| 别 名 | Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335; CD 335; LY94; NCTR1_HUMAN. |
| 研究领域 | 细胞生物 免疫学 信号转导 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD335:198-206/304 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Subunit: Interacts with CD247 and FCER1G Subcellular Location: Cell membrane. Tissue Specificity: Selectively expressed by both resting and activated NK cells. Post-translational modifications: N-glycosylated. O-glycosylated. Similarity: Belongs to the natural cytotoxicity receptor (NCR) family. Contains 2 Ig-like (immunoglobulin-like) domains. SWISS: O76036 Gene ID: 9437 Database links: Entrez Gene: 9437 Human Entrez Gene: 17086 Mouse Omim: 604530 Human SwissProt: O76036 Human SwissProt: Q8C567 Mouse Unigene: 97084 Human Unigene: 240231 Mouse Unigene: 30049 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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