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BN41476R-50ul
50ul
¥1486.00
交叉反应：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41476R-100ul
100ul
¥2360.00
交叉反应：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41476R-200ul
200ul
¥3490.00
交叉反应：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | Calretinin |
| 中文名称 | 钙结合蛋白抗体 |
| 别 名 | 29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR; CALB2_HUMAN; Calretinin. |
| 研究领域 | 神经生物学 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Horse, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Calretinin:211-271/271 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1. Function: Calretinin is a calcium-binding protein which is abundant in auditory neurons. Tissue Specificity: Brain. Similarity: Belongs to the calbindin family. Contains 6 EF-hand domains. SWISS: P22676 Gene ID: 794 Database links: Entrez Gene: 396255 Chicken Entrez Gene: 794 Human Entrez Gene: 12308 Mouse Entrez Gene: 393684 Zebrafish Omim: 114051 Human SwissProt: P07090 Chicken SwissProt: P22676 Human SwissProt: Q08331 Mouse Unigene: 106857 Human Unigene: 2755 Mouse Unigene: 10321 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 钙结合蛋白(Calretinin,CR)主要存在于神经组织中，近10%的腺癌可以表达此蛋白的局部染色阳性，而绝大多数的间皮瘤为阳性表达，因此它是诊断间皮瘤的一个有用的标记物 。 钙结合蛋白是平滑肌和非肌性调控蛋白。它可以与肌动蛋白、肌球蛋白、原肌球蛋白和钙调素相互作用。 |
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