甘油二酯胆碱磷酸转移酶抗体

产品货号：

BN41402R
中文名称：

甘油二酯胆碱磷酸转移酶抗体
英文名称：

Rabbit anti-CHPT1 Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41402R-100ul

100ul

¥2360.00

交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,ELISA
BN41402R-200ul

200ul

¥3490.00

交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,ELISA

产品描述

英文名称	CHPT1
中文名称	甘油二酯胆碱磷酸转移酶抗体
别名	AAPT1-like protein; Cholinephosphotransferase 1; chpt1; CHPT1_HUMAN; Diacylglycerol cholinephosphotransferase 1; hCPT1.
研究领域	肿瘤心血管细胞生物免疫学细胞周期蛋白细胞分化
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	45kDa
细胞定位	细胞浆细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human CHPT1:61-160/406
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS). There are two isoforms of CHPT1 that are produced as a result of alternative splicing events. Function: Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancerous breast epithelial cell lines. Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family. SWISS: Q8WUD6 Gene ID: 56994 Database links: Entrez Gene: 56994 Human SwissProt: Q8WUD6 Human Unigene: 293077 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.