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BN41359R-100ul
100ul
¥2360.00
交叉反应：Human(predicted:Mouse,Rat,Dog,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41359R-200ul
200ul
¥3490.00
交叉反应：Human(predicted:Mouse,Rat,Dog,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
| 英文名称 | PDXK |
| 中文名称 | 吡哆醛激酶抗体 |
| 别 名 | PDXK.1; PDXK_HUMAN; PKH; PNK; Pyridoxal kinase; Pyridoxamine kinase; Pyridoxine kinase; Vitamin B6 kinase. |
| 研究领域 | 细胞生物 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, Dog, Horse, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDXK:101-200/312 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21. Function: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Subunit: Homodimer (Probable). Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitous. Isoform 3 is detected in adult testis and spermatozoa. Similarity: Belongs to the pyridoxine kinase family. SWISS: O00764 Gene ID: 8566 Database links: Entrez Gene: 8566 Human Entrez Gene: 216134 Mouse Omim: 179020 Human SwissProt: O00764 Human SwissProt: Q8K183 Mouse Unigene: 284491 Human Unigene: 206159 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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