货号
产品规格
售价
备注
BN41342R-100ul
100ul
¥2360.00
交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse) 推荐应用:WB,ELISA
BN41342R-200ul
200ul
¥3490.00
交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse) 推荐应用:WB,ELISA
产品描述
英文名称 | ZDHHC-18 |
中文名称 | 锌指蛋白Zdhhc18抗体 |
别 名 | DHHC-18; DKFZp667O2416; Palmitoyltransferase ZDHHC18; ZDH18_HUMAN; Zdhhc18; Zinc finger DHHC domain-containing protein 18. |
研究领域 | 细胞生物 免疫学 信号转导 转录调节因子 锌指蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZDHHC-18:265-360/388 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins. Function: Has palmitoyltransferase activity towards HRAS and LCK. Subcellular Location: Membrane; Multi-pass membrane protein Similarity: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. Contains 1 DHHC-type zinc finger. SWISS: Q9NUE0 Gene ID: 84243 Database links: Entrez Gene: 84243 Human Entrez Gene: 503610 Mouse SwissProt: Q9NUE0 Human SwissProt: Q5Y5T2 Mouse Unigene: 523710 Human Unigene: 331948 Mouse Unigene: 203345 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |