环核苷酸磷酸二酯酶PDE3B抗体

产品货号：

BN41341R
中文名称：

环核苷酸磷酸二酯酶PDE3B抗体
英文名称：

Rabbit anti-PDE3B Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41341R-100ul

100ul

¥2360.00

交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN41341R-200ul

200ul

¥3490.00

交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

产品描述

英文名称	PDE3B
中文名称	环核苷酸磷酸二酯酶PDE3B抗体
别名	5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B cGMP inhibited.
研究领域	细胞生物染色质和核信号信号转导
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, (predicted: Mouse, Rat, Dog, Pig, Horse, Rabbit, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	124kDa
细胞定位	细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human PDE3B:451-550/1112
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation. Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Subcellular Location: Membrane. Tissue Specificity: Abundant in adipose tissues. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. SWISS: Q13370 Gene ID: 5140 Database links: Entrez Gene: 5140 Human Entrez Gene: 18576 Mouse Entrez Gene: 29516 Rat Omim: 602047 Human SwissProt: Q13370 Human SwissProt: Q61409 Mouse SwissProt: Q8CIX5 Mouse SwissProt: Q63085 Rat Unigene: 445711 Human Unigene: 430730 Mouse Unigene: 10322 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.