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GTP酶IMAP家族成员2抗体
  • 产品货号:
    BN41313R
  • 中文名称:
    GTP酶IMAP家族成员2抗体
  • 英文名称:
    Rabbit anti-GIMAP2 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN41313R-100ul

    100ul

    ¥2360.00

    交叉反应:Human 推荐应用:IHC-P,IHC-F,ICC,IF

  • BN41313R-200ul

    200ul

    ¥3490.00

    交叉反应:Human 推荐应用:IHC-P,IHC-F,ICC,IF

产品描述

英文名称GIMAP2
中文名称GTP酶IMAP家族成员2抗体
别    名GTPase, IMAP family member 2; HIMAP2; IMAP2; Immunity associated protein 2; GIMA2_HUMAN.  
研究领域细胞生物  免疫学  G蛋白偶联受体  G蛋白信号  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, 
产品应用IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量38kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GIMAP2:21-120/337 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP2 (GTPase IMAP family member 2), also known as IMAP2 (immunity-associated protein 2) or HIMAP2, is a 337 amino acid multi-pass membrane protein that is encoded by a gene located on human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Function:
Monomer in the presence of bound GDP and in the absence of bound nucleotide. Homodimer in the presence of bound GTP. Can form linear oligomers.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential). Cytoplasm. Note=Detected on the surface of cytoplasmic lipid droplets.

Similarity:
Belongs to the IAN GTP-binding protein family.

SWISS:
Q9UG22

Gene ID:
26157

Database links:

Entrez Gene: 26157 Human

Omim: 608085 Human

SwissProt: Q9UG22 Human

Unigene: 647071 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.