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产品规格
售价
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BN41306R-100ul
100ul
¥2360.00
交叉反应：Rat,Mouse(predicted:Sheep,Horse,Cow,Dog,Chicken,Human) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN41306R-200ul
200ul
¥3490.00
交叉反应：Rat,Mouse(predicted:Sheep,Horse,Cow,Dog,Chicken,Human) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA
产品描述
| 英文名称 | CSMD2 |
| 中文名称 | CSMD2蛋白抗体 |
| 别 名 | CSMD2_HUMAN; CUB and Sushi (SCR repeat) domain; CUB and sushi domain-containing protein 2; CUB and sushi multiple domains protein 2; dJ1007G16.1; dJ1007G16.2; dJ947L8.1; KIAA1884. |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 380kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CSMD2:251-350/3487 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures. Subcellular Location: Cell membrane; Single-pass membrane protein (Potential). Tissue Specificity: Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, hippocampus and fetal brain. Overexpressed in some head and neck cancer cell lines. Similarity: Belongs to the CSMD family. Contains 14 CUB domains. Contains 26 Sushi (CCP/SCR) domains. SWISS: Q7Z408 Gene ID: 114784 Database links: Entrez Gene: 114784 Human Omim: 608398 Human SwissProt: Q7Z408 Human Unigene: 656915 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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