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BN41287R-100ul
100ul
¥2360.00
交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41287R-200ul
200ul
¥3490.00
交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | GAK protein |
| 中文名称 | 细胞周期蛋白G相关激酶抗体 |
| 别 名 | Cyclin G associated kinase; Cyclin-G-associated kinase; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; GAK_HUMAN; MGC99654. |
| 研究领域 | 细胞生物 神经生物学 信号转导 细胞周期蛋白 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 144kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GAK protein:244-330/1311 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. Tissue specificity: Ubiquitous. Highest in testis. Function: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. Subcellular Location: Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion (Probable). Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions. Tissue Specificity: Ubiquitous. Highest in testis. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 C2 tensin-type domain. Contains 1 J domain. Contains 1 phosphatase tensin-type domain. Contains 1 protein kinase domain. SWISS: O14976 Gene ID: 2580 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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