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减数分裂核分裂蛋白1/GAJ抗体
  • 产品货号:
    BN41276R
  • 中文名称:
    减数分裂核分裂蛋白1/GAJ抗体
  • 英文名称:
    Rabbit anti-MND1 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN41276R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41276R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称MND1
中文名称减数分裂核分裂蛋白1/GAJ抗体
别    名GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of antibody; Meiotic nuclear division protein 1 homolog; Meiotic nuclear divisions 1 homolog (S. cerevisiae); Meiotic nuclear divisions 1 homolog; MGC134110; MND1; RGD1309007; 2610034E18Rik; AI591601.  
研究领域细胞生物  细胞周期蛋白  细胞分化  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GAJ/MND1:1-100/205 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.

Function:
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.

Subunit:
Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA.

Subcellular Location:
Nucleus (Probable)

Similarity:
Belongs to the MND1 family.

SWISS:
Q9BWT6

Gene ID:
84057

Database links:

Entrez Gene: 84057 Human

Omim: 611422 Human

SwissProt: Q9BWT6 Human

Unigene: 294088 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.