货号
产品规格
售价
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BN41259R-100ul
100ul
¥2360.00
交叉反应：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Chicken) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41259R-200ul
200ul
¥3490.00
交叉反应：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Chicken) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | MST3/STK3 |
| 中文名称 | 丝氨酸/苏氨酸蛋白激酶3抗体 |
| 别 名 | Kinase responsive to stress 1; KRS1; Mammalian STE20 like protein kinase 2; Mammalian sterile 20-like 2; Mess1; MST; MST-2; MST2; Mst3; Serine/threonine kinase 3 (STE20 homolog, yeast); Serine/threonine kinase 3 (Ste20, yeast homolog); Serine/threonine protein kinase 3; Serine/threonine protein kinase Krs1; STE20 like kinase MST2. |
| 研究领域 | 细胞生物 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human STK3:101-200/491 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Subunit: Homodimer; mediated via the coiled-coil region. Interacts with NORE1, which inhibits autoactivation. Interacts with and stabilizes SAV1. Interacts with RAF1, which prevents dimerization and phosphorylation. Interacts with RASSF1. Interacts (via SARAH domain) with isoform 1 of NEK2. Interacts with ESR1 only in the presence of SAV1. Interacts with PKB/AKT1. Forms a tripartite complex with MOBKL1B and STK38. Interacts with RASSF2 (via SARAH domain). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Expressed at high levels in adult kidney, skeletal and placenta tissues and at very low levels in adult heart, lung and brain tissues. Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 protein kinase domain. Contains 1 SARAH domain. SWISS: Q9Y6E0 Gene ID: 8428 Database links: Entrez Gene: 8428 Human Entrez Gene: 223255 Mouse Omim: 604984 Human SwissProt: Q9Y6E0 Human SwissProt: Q99KH8 Mouse Unigene: 508514 Human Unigene: 390756 Mouse Unigene: 442081 Mouse Unigene: 472866 Mouse Unigene: 105397 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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