货号
产品规格
售价
备注
BN41257R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse(predicted:Rat) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41257R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse(predicted:Rat) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | RHBDD3 |
| 中文名称 | 垂体瘤细胞凋亡抗体 |
| 别 名 | C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3. |
| 研究领域 | 细胞生物 神经生物学 细胞凋亡 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RHBDD3:151-250/386 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Contains 1 UBA domain SWISS: Q9Y3P4 Gene ID: 25807 Database links: Entrez Gene: 25807 Human Entrez Gene: 279766 Mouse SwissProt: Q9Y3P4 Human SwissProt: Q8BP97 Mouse Unigene: 106730 Human Unigene: 260866 Mouse Unigene: 9606 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. RHBDD3分子是一个全新的TLR信号途径的负向调控蛋白分子,是一个能够显著抑制自身免疫性疾病发生的效应分子,RHBDD3控制机体避免发生过度的免疫应答、防止自身免疫性疾病的发生具有重要意义。 |
在线咨询
English
