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细胞表面蛋白CD232抗体
  • 产品货号:
    BN41254R
  • 中文名称:
    细胞表面蛋白CD232抗体
  • 英文名称:
    Rabbit anti-PLXNC1/CD232 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

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  • BN41254R-100ul

    100ul

    ¥2360.00

    交叉反应:nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA

  • BN41254R-200ul

    200ul

    ¥3490.00

    交叉反应:nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA

产品描述

英文名称PLXNC1/CD232
中文名称细胞表面蛋白CD232抗体
别    名CD232; Plexin-C1; PLXC1_HUMAN; Plxnc1; Virus-encoded semaphorin protein receptor.   
研究领域细胞生物  神经生物学  细胞膜受体  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量172kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PLXNC1/CD232:681-780/1568 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]

Function:
Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.

Subcellular Location:
Membrane.

Tissue Specificity:
Detected in heart, brain, lung, spleen and placenta.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the plexin family.
Contains 1 Sema domain.

SWISS:
O60486

Gene ID:
10154

Database links:

Entrez Gene: 10154 Human

Entrez Gene: 54712 Mouse

Omim: 604259 Human

SwissProt: O60486 Human

SwissProt: Q9QZC2 Mouse

Unigene: 584845 Human

Unigene: 256712 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.