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产品规格
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BN41254R-100ul
100ul
¥2360.00
交叉反应:nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA
BN41254R-200ul
200ul
¥3490.00
交叉反应:nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA
产品描述
英文名称 | PLXNC1/CD232 |
中文名称 | 细胞表面蛋白CD232抗体 |
别 名 | CD232; Plexin-C1; PLXC1_HUMAN; Plxnc1; Virus-encoded semaphorin protein receptor. |
研究领域 | 细胞生物 神经生物学 细胞膜受体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 172kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PLXNC1/CD232:681-780/1568 <Extracellular> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011] Function: Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8. Subcellular Location: Membrane. Tissue Specificity: Detected in heart, brain, lung, spleen and placenta. Post-translational modifications: N-glycosylated. Similarity: Belongs to the plexin family. Contains 1 Sema domain. SWISS: O60486 Gene ID: 10154 Database links: Entrez Gene: 10154 Human Entrez Gene: 54712 Mouse Omim: 604259 Human SwissProt: O60486 Human SwissProt: Q9QZC2 Mouse Unigene: 584845 Human Unigene: 256712 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |