雌激素受体相关蛋白α抗体

产品货号：

BN41241R
中文名称：

雌激素受体相关蛋白α抗体
英文名称：

Rabbit anti-ERR-alpha Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41241R-100ul

100ul

¥2360.00

交叉反应：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41241R-200ul

200ul

¥3490.00

交叉反应：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称	ERR-alpha
中文名称	雌激素受体相关蛋白α抗体
别名	Estrogen Related Receptor alpha; ERR-α; ERR α; ERRα; ERR alpha; Err 1; ERR a; ERR alpha; ERR-alpha; Err1; ERR1_HUMAN; ERRa; ERRalpha; ESRL 1; ESRL1; ESRR A; Esrra; Estrogen receptor like 1; Estrogen receptor related 1; Estrogen receptor-like 1; Estrogen related receptor alpha; Estrogen-related receptor alpha; Estrra; Nr3b1; Nuclear receptor subfamily 3 group B member 1; Steroid hormone receptor ERR1.
研究领域	肿瘤细胞生物染色质和核信号信号转导生长因子和激素结合蛋白细胞骨架表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	47kDa
细胞定位	细胞核
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Estrogen Related Receptor alpha:101-200/423
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Subunit: Binds DNA as a monomer or a homodimer. Interacts (via the AF2 domain) with coactivator PPARGC1A (via the L3 motif); the interaction greatly enhances transriptional activity of genes involved in energy metabolism. Interacts with PIAS4; the interaction enhances sumoylation. Subcellular Location: Nucleus. Similarity: Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. SWISS: P11474 Gene ID: 2101 Database links: Entrez Gene: 2101 Human Entrez Gene: 26379 Mouse Entrez Gene: 293701 Rat Omim: 601998 Human SwissProt: P11474 Human SwissProt: O08580 Mouse SwissProt: Q5QJV7 Rat Unigene: 110849 Human Unigene: 386776 Mouse Unigene: 130171 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.