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维甲酸相关孤儿受体β抗体
  • 产品货号:
    BN41200R
  • 中文名称:
    维甲酸相关孤儿受体β抗体
  • 英文名称:
    Rabbit anti-ROR beta Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN41200R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Cow,Horse,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41200R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Cow,Horse,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称ROR beta
中文名称维甲酸相关孤儿受体β抗体
别    名bA133M9.1; NR1F2; Nuclear receptor ROR-beta; Nuclear receptor RZR beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; OTTHUMP00000021486; RAR related orphan receptor B; RAR related orphan receptor beta; Retinoic acid binding receptor beta; Retinoid-related orphan receptor-beta; ROR BETA; Rorb; RORB_HUMAN; RZR BETA; RZRB.   
研究领域肿瘤  细胞生物  染色质和核信号  神经生物学  信号转导  细胞周期蛋白  细胞分化  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RORB:385-470/470 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍ROR beta is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.

Function:
Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter (By similarity).

Subcellular Location:
Nucleus (Probable).

Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

SWISS:
Q92753

Gene ID:
6096

Database links:

Entrez Gene: 6096 Human

Entrez Gene: 225998 Mouse

Entrez Gene: 309288 Rat

Omim: 601972 Human

SwissProt: Q92753 Human

SwissProt: Q8R1B8 Mouse

SwissProt: P45446 Rat

Unigene: 494178 Human

Unigene: 234641 Mouse

Unigene: 210157 Rat

Unigene: 231652 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.