货号
产品规格
售价
备注
BN41192R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,ELISA
BN41192R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,ELISA
产品描述
英文名称 | SESN3 |
中文名称 | Sestrin3抗体 |
别 名 | SESN3; SESN3_HUMAN; SEST3; Sestrin 3; Sestrin-3. |
研究领域 | 肿瘤 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 54kDa |
细胞定位 | 细胞核 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SESN3:401-492/492 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] Subcellular Location: Widely expressed. Similarity: Belongs to the sestrin family. SWISS: P58005 Gene ID: 143686 Database links: Entrez Gene: 143686 Human Entrez Gene: 75747 Mouse Omim: 607768 Human SwissProt: P58005 Human SwissProt: Q9CYP7 Mouse Unigene: 659934 Human Unigene: 325126 Mouse Unigene: 439776 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |