5'肌苷磷酸脱氢酶2抗体

产品货号：

BN41177R
中文名称：

5'肌苷磷酸脱氢酶2抗体
英文名称：

Rabbit anti-IMPDH2 Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41177R-100ul

100ul

¥2360.00

交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41177R-200ul

200ul

¥3490.00

交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称	IMPDH2
中文名称	5'肌苷磷酸脱氢酶2抗体
别名	IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP oxireductase 2; IMPD 2; IMPD2; IMPDH 2; IMPDH II; IMPDH-II; Impdh2; IMPDHII; Inosine 5' monophosphate dehydrogenase 2; Inosine-5''-monophosphate dehydrogenase 2; IMDH2_HUMAN.
研究领域	肿瘤免疫学信号转导生长因子和激素
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	56kDa
细胞定位	细胞核细胞浆
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human IMPDH2:441-514/514
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. Function: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. Subunit: Homotetramer. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the IMPDH/GMPR family. Contains 2 CBS domains. SWISS: P12268 Gene ID: 3615 Database links: Entrez Gene: 3615 Human Entrez Gene: 23918 Mouse Entrez Gene: 301005 Rat Omim: 146691 Human SwissProt: P12268 Human SwissProt: P24547 Mouse SwissProt: E9PU28 Rat Unigene: 654400 Human Unigene: 6065 Mouse Unigene: 8093 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.