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BN41169R-100ul
100ul
¥2360.00
交叉反应：Mouse(predicted:Human,Rat) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41169R-200ul
200ul
¥3490.00
交叉反应：Mouse(predicted:Human,Rat) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | KLST/Kallistatin |
| 中文名称 | 激肽释放酶抑制剂抗体 |
| 别 名 | Serpin peptidase inhibitor clade A member 4; Kallikrein binding protein; Kallikrein inhibitor; Protease inhibitor 4; Serpin A4; KAL; Kallikrein binding protein; Kallikrein inhibitor; KBP; KLST; KST; MGC108582; PI4; Protease inhibitor 4; Serpin A4; Serpin peptidase inhibitor clade A member 4; SERPINA4; KAIN_HUMAN. |
| 研究领域 | 心血管 细胞生物 免疫学 生长因子和激素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLST/Kallistatin:151-250/427 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity. Function: Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Subunit: Monomer and some homodimers. Subcellular Location: Secreted. Tissue Specificity: Expressed by the liver and secreted in plasma. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the serpin family. SWISS: P29622 Gene ID: 5267 Database links: Entrez Gene: 5267 Human Omim: 147935 Human SwissProt: P29622 Human Unigene: 719893 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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