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驱动蛋白结合蛋白1抗体
  • 产品货号:
    BN41138R
  • 中文名称:
    驱动蛋白结合蛋白1抗体
  • 英文名称:
    Rabbit anti-TRAK1 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

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  • BN41138R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推荐应用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41138R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推荐应用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

产品描述

英文名称TRAK1
中文名称驱动蛋白结合蛋白1抗体
别    名106 kDa O-GlcNAc transferase-interacting protein; 106 kDa O GlcNAc transferase interacting protein; KIAA1042; OGT(O Glc NAc transferase) interacting protein 106 KDa; OIP106; TRAK1_HUMAN; Trafficking kinesin binding protein 1; Trafficking kinesin-binding protein 1; Trafficking protein kinesin binding 1; TRAK 1.   
研究领域肿瘤  免疫学  信号转导  细胞骨架  肿瘤细胞生物标志物  线粒体  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量106kDa
细胞定位细胞核 细胞浆 线粒体
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human TRAK1:171-270/953 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The specific function of TRAK1 remains unknown. It interacts with O-GlcNAc transferase, RHOT1/Miro-1 and RHOT2/Miro-2. It shows high expression in spinal cord and moderate expression in all other tissues and specific brain regions examined.

Function:
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors.

Subunit:
Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Interacts with HGS. Interacts with GABRA1. Interacts with KIF5C.

Subcellular Location:
Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome.

Tissue Specificity:
High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.

Post-translational modifications:
O-glycosylated.

Similarity:
Contains 1 HAP1 N-terminal domain.

SWISS:
Q9UPV9

Gene ID:
22906

Database links:

Entrez Gene: 22906 Human

Omim: 608112 Human

SwissProt: Q9UPV9 Human

Unigene: 535711 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.