Bcl-2结合抑凋亡蛋白2抗体

产品货号：

BN41044R
中文名称：

Bcl-2结合抑凋亡蛋白2抗体
英文名称：

Rabbit anti-BAG2 Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41044R-100ul

100ul

¥2360.00

交叉反应：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41044R-200ul

200ul

¥3490.00

交叉反应：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

产品描述

英文名称	BAG2
中文名称	Bcl-2结合抑凋亡蛋白2抗体
别名	BAG 2; BAG-2; BAG family molecular chaperone regulator 2; BAG-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; dJ417I1.2; KIAA0576; MGC149462.
研究领域	肿瘤免疫学信号转导细胞凋亡转录调节因子
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Horse, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	24kDa
细胞定位	细胞浆
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human BAG2:151-211/211
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]. Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Similarity: Contains 1 BAG domain. SWISS: O95816 Gene ID: 9532 Database links: Entrez Gene: 9532 Human Omim: 603882 Human SwissProt: O95816 Human Unigene: 55220 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.