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产品规格
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BN41042R-100ul
100ul
¥2360.00
交叉反应：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41042R-200ul
200ul
¥3490.00
交叉反应：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | Cytochrome b5 |
| 中文名称 | 细胞色素b5抗体 |
| 别 名 | CYB 5; CYB 5A; CYB5; CYB5_HUMAN; CYB5A; Cytochrome b 5; Cytochrome b5 (microsomal); Cytochrome b5; Cytochrome b5 type A (microsomal); Cytochrome b5 type A; MCB 5; MCB5; Microsomal cytochrome b5; Microsomal cytochrome b5 type A; Type 1 cyt b5; CYB5A. |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 新陈代谢 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15kDa |
| 细胞定位 | 细胞浆 细胞膜 线粒体 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cytochrome b5:9-80/134 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Function: Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. Subcellular Location: Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side. Isoform 2: Cytoplasm. DISEASE: Methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]: A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the cytochrome b5 family. Contains 1 cytochrome b5 heme-binding domain. SWISS: P00167 Gene ID: 1528 Database links: Entrez Gene: 1528 Human Entrez Gene: 109672 Mouse Omim: 250790 Human Omim: 613218 Human SwissProt: P00167 Human SwissProt: P56395 Mouse SwissProt: Q544Z9 Mouse Unigene: 465413 Human Unigene: 31018 Mouse Unigene: 1055 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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