货号
产品规格
售价
备注
BN41041R-100ul
100ul
¥2360.00
交叉反应：Rat(predicted:Human,Mouse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41041R-200ul
200ul
¥3490.00
交叉反应：Rat(predicted:Human,Mouse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
产品描述
| 英文名称 | PNPO |
| 中文名称 | 磷酸吡哆醇氧化酶抗体 |
| 别 名 | PDXPO; PNPO; PNPO_HUMAN; Pyridoxal 5' phosphate synthase; pyridoxamine 5' phosphate oxidase; Pyridoxamine phosphate oxidase; Pyridoxamine-phosphate oxidase; pyridoxine 5' phosphate oxidase; Pyridoxine-5''-phosphate oxidase; EC 1.4.3.5; FLJ10535. |
| 研究领域 | 肿瘤 细胞生物 免疫学 转录调节因子 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Rat, (predicted: Human, Mouse, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PNPO:41-140/261 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). Function: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). Subunit: Homodimer. DISEASE: Defects in PNPO are the cause of pyridoxine-5'-phosphate oxidase deficiency (PNPO deficiency) [MIM:610090]; also known as PNPO-related neonatal epileptic encephalopathy. The main feature of neonatal epileptic encephalopathy is the onset within hours of birth of a severe seizure disorder that does not respond to anticonvulsant drugs and can be fatal. Seizures can cease with the administration of PLP, being resistant to treatment with pyridoxine. Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family. SWISS: Q9NVS9 Gene ID: 55163 Database links: Entrez Gene: 55163 Human Entrez Gene: 103711 Mouse Omim: 603287 Human SwissProt: Q9NVS9 Human SwissProt: Q91XF0 Mouse Unigene: 631742 Human Unigene: 254704 Mouse Unigene: 158883 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PNPO是维生素B6(VB6)代谢的关键酶，参与催化氨基酸代谢的各种反应和其它多种代谢过程。 |
在线咨询
English
