货号
产品规格
售价
备注
BN40973R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA
BN40973R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA
产品描述
英文名称 | eIF3A |
中文名称 | 真核翻译起始因子3A抗体 |
别 名 | centrosomin homolog; cytoplasmic protein p167; eIF 3 theta; eIF-3-theta; EIF3; eIF3 p167; eIF3 p170; eIF3 p180; EIF3 p180 subunit; eIF3 p185; eIF3 theta; eIF3a; EIF3S10; eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD); eukaryotic translation initiation factor 3 subunit 10 (theta 170kD); eukaryotic translation initiation factor 3 subunit 10 170kDa; Eukaryotic translation initiation factor 3 subunit 10; eukaryotic translation initiation factor 3 subunit 10 theta 150 170kDa; Eukaryotic translation initiation factor 3 subunit A; P167; p180; p185; TIF32. |
研究领域 | 肿瘤 免疫学 信号转导 转录调节因子 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 166kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human eIF3A:801-900/1382 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Subcellular Location: Cytoplasm. Similarity: Belongs to the eIF-3 subunit A family. Contains 1 PCI domain. SWISS: Q14152 Gene ID: 8661 Database links: Entrez Gene: 8661 Human Entrez Gene: 13669 Mouse Omim: 602039 Human SwissProt: Q14152 Human SwissProt: P23116 Mouse Unigene: 523299 Human Unigene: 713331 Human Unigene: 2238 Mouse Unigene: 482533 Mouse Unigene: 1644 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |