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真核翻译起始因子3A抗体
  • 产品货号:
    BN40973R
  • 中文名称:
    真核翻译起始因子3A抗体
  • 英文名称:
    Rabbit anti-eIF3A Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN40973R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN40973R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称eIF3A
中文名称真核翻译起始因子3A抗体
别    名centrosomin homolog; cytoplasmic protein p167; eIF 3 theta; eIF-3-theta; EIF3; eIF3 p167; eIF3 p170; eIF3 p180; EIF3 p180 subunit; eIF3 p185; eIF3 theta; eIF3a; EIF3S10; eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD); eukaryotic translation initiation factor 3 subunit 10 (theta 170kD); eukaryotic translation initiation factor 3 subunit 10 170kDa; Eukaryotic translation initiation factor 3 subunit 10; eukaryotic translation initiation factor 3 subunit 10 theta 150 170kDa; Eukaryotic translation initiation factor 3 subunit A; P167; p180; p185; TIF32.  
研究领域肿瘤  免疫学  信号转导  转录调节因子  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量166kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human eIF3A:801-900/1382 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the eIF-3 subunit A family.
Contains 1 PCI domain.

SWISS:
Q14152

Gene ID:
8661

Database links:

Entrez Gene: 8661 Human

Entrez Gene: 13669 Mouse

Entrez Gene: 292148 Rat

Omim: 602039 Human

SwissProt: Q14152 Human

SwissProt: P23116 Mouse

SwissProt: Q1JU68 Rat

Unigene: 523299 Human

Unigene: 713331 Human

Unigene: 2238 Mouse

Unigene: 482533 Mouse

Unigene: 1644 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.









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