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粒细胞-巨噬细胞克隆刺激因子抗体
  • 产品货号:
    BN40964R
  • 中文名称:
    粒细胞-巨噬细胞克隆刺激因子抗体
  • 英文名称:
    Rabbit anti-GM-CSF Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN40964R-100ul

    100ul

    ¥2360.00

    交叉反应:Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN40964R-200ul

    200ul

    ¥3490.00

    交叉反应:Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN40964R-50ul

    50ul

    ¥1486.00

    交叉反应:Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称GM-CSF
中文名称粒细胞-巨噬细胞克隆刺激因子抗体
别    名Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN.   




研究领域肿瘤  免疫学  信号转导  趋化因子  细胞表面分子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Recombinant protein)
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量14kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GM-CSF:65-144/144 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008].

Function:
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Subunit:
Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.

Subcellular Location:
Secreted.

Similarity:
Belongs to the GM-CSF family.

SWISS:
P04141

Gene ID:
1437

Database links:

Entrez Gene: 1437 Human

Omim: 138960 Human

SwissProt: P04141 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GM-CSF是血管内皮细胞、单核细胞和成纤维细胞合成的糖蛋白。能促进中性粒细胞成熟;刺激成熟的粒细胞从骨髓释出;增强中性粒细胞趋化及吞噬功能。














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