最近搜索:细胞培养 微生物学 分子生物 生物化学
首页>>免疫学>>一抗>>中介素抗体
中介素抗体
  • 产品货号:
    BN40840R
  • 中文名称:
    中介素抗体
  • 英文名称:
    Rabbit anti-ADM2 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN40840R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Horse,Rabbit) 推荐应用:IHC-P,IHC-F,IF,ELISA

  • BN40840R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Horse,Rabbit) 推荐应用:IHC-P,IHC-F,IF,ELISA

产品描述

英文名称ADM2
中文名称中介素抗体
别    名ADM2; IMD; Intermedin; Adrenomedullin-2; AM2; IMDL; IMDS; ADM2_HUMAN; Adrenomedullin 2; dJ579N16.4; FLJ21135; IMDL; Intermedin-long; Intermedin-short.   
研究领域心血管  细胞生物  免疫学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Pig, Horse, Rabbit, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量5.2kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Intermedin:75-148/148 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a protein which is a member of the calcitonin-related hormones. The encoded protein is involved in maintaining homeostasis in many tissues, acting via CRLR/RAMP receptor (calcitonin receptor-like receptor/receptor activity-modifying protein) complexes. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
TISSUE SPECIFICITY:High expression detected in the submaxillary gland, kidney, stomach, and mesentery, followed by the pituitary, lung, pancreas, intestines, spleen, thymus and ovary. Expressed mainly in the intermediate lobe of the pituitary, with sporadic in the anterior lobe.

Function:
IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary.

Similarity:
Belongs to the adrenomedullin family.

SWISS:
Q7Z4H4

Gene ID:
79924

Database links:

Entrez Gene: 79924 Human

Entrez Gene: 223780 Mouse

Entrez Gene: 399475 Rat

Omim: 608682 Human

SwissProt: Q7Z4H4 Human

SwissProt: Q7TNK8 Mouse

SwissProt: P61312 Rat

Unigene: 449099 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













image.png

image.png

image.png