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荷尔蒙敏感脂肪酶抗体
  • 产品货号:
    BN40729R
  • 中文名称:
    荷尔蒙敏感脂肪酶抗体
  • 英文名称:
    Rabbit anti-HSL/LIPE Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN40729R-100ul

    100ul

    ¥2360.00

    交叉反应:Rat(predicted:Human,Mouse,Pig,Cow,Sheep) 推荐应用:IHC-P

  • BN40729R-200ul

    200ul

    ¥3490.00

    交叉反应:Rat(predicted:Human,Mouse,Pig,Cow,Sheep) 推荐应用:IHC-P

产品描述

英文名称HSL/LIPE
中文名称荷尔蒙敏感脂肪酶抗体
别    名Hormone sensitive lipase; hormone-sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE; Hormone-sensitive lipase; LIPS_HUMAN.  
研究领域心血管  免疫学  生长因子和激素  糖尿病  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Rat,  (predicted: Human, Mouse, Pig, Cow, Sheep, )
产品应用IHC-P=1:400-800 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量116kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HSL/LIPE :441-540/1076 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍HSL ( hormone- sensitive lipase ) is an enzyme involved in hydrolysis of stored triglycerides and fatty acids; important for regulation of energy homeostasis. It has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.

Function:
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

Subunit:
Interacts with PTRF in the adipocyte cytoplasm.

Subcellular Location:
Cell membrane. Membrane, caveola. Cytoplasm, cytosol.

Similarity:
Belongs to the 'GDXG' lipolytic enzyme family.

SWISS:
Q05469

Gene ID:
3991

Database links:

Entrez Gene: 3991 Human

Entrez Gene: 16890 Mouse

Entrez Gene: 25330 Rat

Omim: 151750 Human

SwissProt: Q05469 Human

SwissProt: Q6NSL7 Human

SwissProt: P54310 Mouse

SwissProt: P15304 Rat

Unigene: 656980 Human

Unigene: 158548 Mouse

Unigene: 333679 Mouse

Unigene: 10566 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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