血管内皮生长因子C型抗体

产品货号：

BN40639R
中文名称：

血管内皮生长因子C型抗体
英文名称：

Rabbit anti-VEGF-C Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN40639R-100ul

100ul

¥2360.00

交叉反应：Human,Mouse(predicted:Rat,Pig,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN40639R-200ul

200ul

¥3490.00

交叉反应：Human,Mouse(predicted:Rat,Pig,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

产品描述

英文名称	VEGF-C
中文名称	血管内皮生长因子C型抗体
别名	Vascuoar endothelial growth factor-C; AW228853; Flt4 ligand; Flt4-L; VEGF2; VEGFC; VRP; VEGFC_HUMAN.
研究领域	细胞生物血管内皮细胞
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, (predicted: Rat, Pig, Horse, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	13/46kDa
细胞定位	分泌型蛋白
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human VEGF-C:112-170/419
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. Subunit: Homodimer; non-covalent and antiparallel. Subcellular Location: Secreted. Tissue Specificity: Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Similarity: Belongs to the PDGF/VEGF growth factor family. SWISS: P49767 Gene ID: 7424 Database links: Entrez Gene: 7424 Human Entrez Gene: 22341 Mouse Entrez Gene: 114111 Rat Omim: 601528 Human SwissProt: P49767 Human SwissProt: P97953 Mouse SwissProt: O35757 Rat Unigene: 435215 Human Unigene: 1402 Mouse Unigene: 6913 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.