货号
产品规格
售价
备注
BN40618R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse(predicted:Rat) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN40618R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse(predicted:Rat) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
产品描述
英文名称 | CD90 |
中文名称 | CD90抗体 |
别 名 | CD90 / Thy1; CD7; CD90 antigen; CDw90; FLJ33325; MGC128895; T25; Theta antigen; Thy-1; Thy 1; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1 membrane glycoprotein precursor; Thy 1.2; Thy-1 T-cell antigen; Thy1 antigen; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta; THY1_RAT; THY1_HUMAN. |
研究领域 | 细胞生物 免疫学 神经生物学 t-淋巴细胞 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, (predicted: Rat, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 12kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CD90:20-100/161 <Extracellular> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to some of the initial biochemical description and characterization of a vertebrate GPI anchor and also the first demonstration of tissue specific differential glycosylation. Function: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Abundant in lymphoid tissues. Post-translational modifications: Glycosylation is tissue specific. Sialylation of N-glycans at Asn-93 in brain and at Asn-42, Asn-93 and Asn-117 in thymus. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: P04216 Gene ID: 7070 Database links: Entrez Gene: 7070 Human Entrez Gene: 21838 Mouse Omim: 188230 Human SwissProt: P04216 Human SwissProt: P01831 Mouse Unigene: 644697 Human Unigene: 3951 Mouse Unigene: 108198 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Thy1/CD90主要表达于脑和淋巴组织,包括胸腺细胞、外周血液T细胞和一些上皮内层T细胞。 Thy-1是一种糖基磷酸酯酰醇(GPI)固定的表面糖蛋白,Thy-1在T细胞激活、神经系统发育及其发挥功能、细胞程序性死亡等方面发挥作用。 |