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售价
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BN40518R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse,Rat,Dog 推荐应用:WB,ELISA
BN40518R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse,Rat,Dog 推荐应用:WB,ELISA
产品描述
英文名称 | LRTOMT/LRRC51 |
中文名称 | 富含亮氨酸重复蛋白51抗体 |
别 名 | COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1. |
研究领域 | 细胞生物 免疫学 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Mouse, Rat, hu, mo, rat, dog) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LRTOMT/LRRC51:1-100/192 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012] Subcellular Location: Cytoplasmic Similarity: Contains 3 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. SWISS: Q96E66 Gene ID: 220074 Database links: Entrez Gene: 220074 Human Entrez Gene: 69358 Mouse Omim: 612414 Human SwissProt: Q96E66 Human SwissProt: Q9DAK8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |