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产品规格
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BN40505R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA
BN40505R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA
产品描述
| 英文名称 | SP2 transcription factor |
| 中文名称 | 转录因子Sp2抗体 |
| 别 名 | Kiaa0048; OTTHUMP00000196580; SP2; SP2_HUMAN; SPECIFICITY PROTEIN 2; Transcription factor Sp2. |
| 研究领域 | 转录调节因子 结合蛋白 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 65kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SP2 transcription factor:341-440/613 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008] Function: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Subcellular Location: Nucleus. Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. SWISS: Q02086 Gene ID: 6668 Database links: Entrez Gene: 6668 Human Entrez Gene: 78912 Mouse Omim: 601801 Human SwissProt: Q02086 Human SwissProt: Q9D2H6 Mouse Unigene: 514276 Human Unigene: 482333 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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