货号
产品规格
售价
备注
BN40381R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse 推荐应用:WB,IHC-P,IHC-F,ICC,IF
BN40381R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse 推荐应用:WB,IHC-P,IHC-F,ICC,IF
产品描述
英文名称 | PFDN3 |
中文名称 | 希佩尔-林道结合蛋白抗体 |
别 名 | HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1; Von Hippel-Lindau-binding protein 1. |
研究领域 | 细胞生物 信号转导 转录调节因子 结合蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, |
产品应用 | WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 23kDa |
细胞定位 | 细胞核 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PFDN3:51-150/197 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015] Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Subcellular Location: Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus. Tissue Specificity: Ubiquitous. Similarity: Belongs to the prefoldin subunit alpha family. SWISS: P61758 Gene ID: 7411 Database links: Entrez Gene: 7411 Human Entrez Gene: 22327 Mouse Omim: 300133 Human SwissProt: P61758 Human SwissProt: P61759 Mouse Unigene: 436803 Human Unigene: 8294 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |