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| 英文名称 | P2Y1 |
| 中文名称 | P2Y1受体抗体/嘌呤受体抗体 |
| 别 名 | ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1; P2RY1_HUMAN; P2Y1 purinoceptor. |
| 研究领域 | 信号转导 转录调节因子 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, (predicted: Human, Chicken, Dog, Cow, Horse, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P2Y1R:285-373/373 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008] Function: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P47900 Gene ID: 5028 Database links: Entrez Gene: 100135592 Guinea pig Entrez Gene: 5028 Human Entrez Gene: 18441 Mouse Omim: 601167 Human SwissProt: P59902 Guinea pig SwissProt: P47900 Human SwissProt: P49650 Mouse Unigene: 654526 Human Unigene: 281452 Mouse Unigene: 10217 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. P2Y1 receptor 为离子通道蛋白，一种受体配体开启的离子通道，介导细胞外核苷酸细胞间信号传导 |
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